One of the clearest signs of aging is the development of wrinkles in the face. Wrinkles can be either static with contributing factors such as sun damage, age and gravity, or dynamic or expression lines that are caused by facial movements by mimetic muscles, that is, they are the result of repeated muscle contractions.
One of the best solutions to correct expression lines is to apply Vistabel® which causes a reversible paralysis of the muscles responsible for the formation of such wrinkles. Since the rest of facial muscles are not treated, facial expression remains the same without alterations.
How does it work?
When injected into the muscle, Botulinum toxin A acts on the neuromuscular junction blocking the release of acetylcholine, a substance responsible for transmitting the nerve impulse towards the muscle, thus preventing its contraction and causing its relaxation. Hence, the skin situated above the treated muscle remains smooth and no wrinkles are formed.
The intramuscular injection of Vistabel® produces a reduction of muscle contraction that is dose-dependent. The therapeutic effects starts to become noticeable 48 to 72 hours after administration, with a total effect being achieved between the first and second week. Muscle functionality is restored between four and six months later with a loss of the effect.
The paralysis of the muscle induced by the toxin is reversible. The application of Vistabel® does not require anaesthesia, it is performed on an outpatient basis and the patient can resume daily activities immediately. The only precaution that needs to be taken is to maintain the head lifted for about four hours and to avoid massaging the treated area until the next day.
Vistabel® is indicated in patients with neuromuscular disorders such as myasthenia gravis and in Eaton Lambert´s syndrome, in pregnancy and breastfeeding, and in patients with allergy to albumin.
Side effects are rare. A small haematoma or small inflammation may appear at the injection sites if a capillary vessel is accidentally punctures; however, these usually fade away in just a few days. The paralysis of other adjoining muscles, such as the dropping of an eyebrow, is rare and if it does happen, it is usually transient and totally reversible.
Vistabel® can only be injected in medical centres with a medication depository that are authorised and accredited by the Ministry of Health.